HCID 67428928, compound → HCID 59867953, compound

HRID 1662720Notes

Reaction equation

HRID 1662720 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[C:5]2([N:21]1[CH2:30][C@H:29]([O:31][CH2:32][CH2:33][C:34]#[N:35])[CH2:28][C@H:22]1[C:23]([N:25]([CH3:27])[CH3:26])=[O:24])[C:12]1[CH:17]=[C:16]([CH3:18])[CH:15]=[CH:14][C:13]=1[O:19][CH3:20].[CH3:36][O:37][C:38]1[CH:43]=[CH:42][C:41]([S:44](Cl)(=[O:46])=[O:45])=[C:40]([O:48][C:49]([F:52])([F:51])[F:50])[CH:39]=1>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([S:44]([C:41]1[CH:42]=[CH:43][C:38]([O:37][CH3:36])=[CH:39][C:40]=1[O:48][C:49]([F:50])([F:51])[F:52])(=[O:46])=[O:45])[C:6](=[O:11])[C:5]2([N:21]1[CH2:30][C@H:29]([O:31][CH2:32][CH2:33][C:34]#[N:35])[CH2:28][C@H:22]1[C:23]([N:25]([CH3:27])[CH3:26])=[O:24])[C:12]1[CH:17]=[C:16]([CH3:18])[CH:15]=[CH:14][C:13]=1[O:19][CH3:20]

Participants

3

Reactant 2

HCID 67428928HCID 67428928, compoundHCID 866256844-Methoxy-2-(trifluoromethoxy)benzene sulfonyl chloride

Product 1

HCID 59867953HCID 59867953, compoundYield 66.2%

Procedure

With 720 mg of the compound obtained in Step 143-4 and 506 mg of 4-methoxy-2-(trifluoromethoxy)benzene sulfonyl chloride as starting materials, 720 mg of the title compound (amorphous) was obtained by a similar procedure to Example 2.

Sources & evidence

ORD record
ord-a3f70d14e5074c36942b321f920d28a3
Source dataset
uspto-grants-2011_10
Patent number
US08030499B2

Reaction notes

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