HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-chloro-1H-indole-2,3-dione → 5-chloro-3-hydroxy-3-[2-(methylthio) phenyl]-1,3-dihydro-2H-indol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-chloro-1H-indole-2,3-dione | HCID 87203 | — |
| Reactant | 2-Bromothioanisole | HCID 88166 | — |
| Product | 5-chloro-3-hydroxy-3-[2-(methylthio) phenyl]-1,3-dihydro-2H-indol-2-one | HCID 67429669 | 66.3% |
Reaction Steps
With 15.0 g of 1-bromo-2-(methylthio) benzene and 10.3 g of 5-chloroisatin as starting materials, 11.5 g of the title compound (orange red solid) was obtained by a similar method to Step 21-1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030499B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-c0f63b2647144bb5972a8db198c5ebec |
| Source note | uspto-grants-2011_10 |