HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanamine, N-methoxy-, hydrochloride (1:1) → (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxopropan-2-yl)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanamine, N-methoxy-, hydrochloride (1:1) | HCID 81138 | — |
| Reactant | Tert-butoxycarbonylalanine | HCID 85082 | — |
| Product | (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxopropan-2-yl)carbamate | HCID 11806530 | 52.5% |
Reaction Steps
With 2.00 g of N-(tert-butoxy carbonyl)-L-alanine and 1.55 g of N,O-dimethyl hydroxylamine hydrochloride as starting materials, 1.29 g of the title compound (colorless solid) was obtained by a similar procedure to Step 10-1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030499B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-582b8a496d8c46e9a24c66b8e8e7234d |
| Source note | uspto-grants-2011_10 |