HCID 67428719, compound → HCID 59867828, compound

HRID 1662789Notes

Reaction equation

HRID 1662789 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[C:5]2([NH:20][C:21]([CH3:28])([CH3:27])[C:22]([N:24]([CH3:26])[CH3:25])=[O:23])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[O:18][CH3:19].[CH3:29][O:30][C:31]1[CH:36]=[CH:35][C:34]([S:37](Cl)(=[O:39])=[O:38])=[C:33]([O:41][C:42]([F:45])([F:44])[F:43])[CH:32]=1>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([S:37]([C:34]1[CH:35]=[CH:36][C:31]([O:30][CH3:29])=[CH:32][C:33]=1[O:41][C:42]([F:43])([F:44])[F:45])(=[O:39])=[O:38])[C:6](=[O:11])[C:5]2([NH:20][C:21]([CH3:28])([CH3:27])[C:22]([N:24]([CH3:25])[CH3:26])=[O:23])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[O:18][CH3:19]

Participants

3

Reactant 2

HCID 67428719HCID 67428719, compoundHCID 866256844-Methoxy-2-(trifluoromethoxy)benzene sulfonyl chloride

Product 1

HCID 59867828HCID 59867828, compoundYield 45.6%

Procedure

With 0.51 g of the compound obtained in Step 255-4 and 378 mg of 4-methoxy-2-(trifluoromethoxy)benzene sulfonyl chloride as starting materials, 0.38 g of the title compound (colorless solid) was obtained by a similar procedure to Example 2.

Sources & evidence

ORD record
ord-af3ef04cc88d4f529ff10d9b95d84088
Source dataset
uspto-grants-2011_10
Patent number
US08030499B2

Reaction notes

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