5-Methylisatin → HCID 67429312, compound

HRID 1662795Notes

Reaction equation

HRID 1662795 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5](Br)[CH:6]=[CH:7][CH:8]=1.[CH3:10][C:11]1[CH:12]=[C:13]2[C:17](=[CH:18][CH:19]=1)[NH:16][C:15](=[O:20])[C:14]2=[O:21]>>[OH:21][C:14]1([C:5]2[CH:6]=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[CH:4]=2)[C:13]2[C:17](=[CH:18][CH:19]=[C:11]([CH3:10])[CH:12]=2)[NH:16][C:15]1=[O:20]

Participants

3

Reactant 2

HCID 118405-MethylisatinHCID 169713-Bromoanisole

Product 1

HCID 67429312HCID 67429312, compoundYield 94.3%

Procedure

With 5.61 g of 3-methoxy bromobenzene and 3.23 g of 5-methyl isatin as starting materials, 5.09 g of the title compound was obtained by a similar method to Step 21-1.

Sources & evidence

ORD record
ord-9a258909464a47c182df2b9f8b6ac9ed
Source dataset
uspto-grants-2011_10
Patent number
US08030499B2

Reaction notes

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