4-Chloroisatin → HCID 67429107, compound

HRID 1662797Notes

Reaction equation

HRID 1662797 reaction equation
Br[C:2]1[C:10]2[O:9][CH2:8][O:7][C:6]=2[CH:5]=[CH:4][CH:3]=1.[Cl:11][C:12]1[CH:20]=[CH:19][CH:18]=[C:17]2[C:13]=1[C:14](=[O:22])[C:15](=[O:21])[NH:16]2>>[O:7]1[C:6]2[CH:5]=[CH:4][CH:3]=[C:2]([C:14]3([OH:22])[C:13]4[C:17](=[CH:18][CH:19]=[CH:20][C:12]=4[Cl:11])[NH:16][C:15]3=[O:21])[C:10]=2[O:9][CH2:8]1

Participants

3

Reactant 2

HCID 960474-ChloroisatinHCID 27761894-Bromo-1,3-benzodioxole

Product 1

HCID 67429107HCID 67429107, compoundYield 43.9%

Procedure

With 9.00 g of 4-bromo-1,3-benzodioxol and 1.81 g of 4-chloroisatin as starting materials, 1.33 g of the title compound was obtained by a similar method to Step 21-1.

Sources & evidence

ORD record
ord-b99ed6f28ed3424f990d2b75c282b9b7
Source dataset
uspto-grants-2011_10
Patent number
US08030499B2

Reaction notes

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