Trimethylsilyl iodide → 3,4-Diphosphonothiophene

Participants

Reaction Steps

In acetonitrile, 0.200 g (0.561 mmols) of 3,4-bis(diethoxyphosphoryl)thiophene was dissolved, to which 0.5613 g (2.805 mmols) of commercially available iodotrimethylsilane was added at room temperature. Thereafter, the mixture was stirred at room temperature for 12 hours. After the reaction, the solvent was removed by distilling off under reduced pressure, followed by addition of methanol and stirring at room temperature for further 12 hours. The methanol was removed by distilling off under reduced pressure, followed by addition of distilled water under stirring and separation of an aqueous phase. The thus separated aqueous phase was washed several times with chloroform and the aqueous phase was concentrated and evaporated to dryness to obtain the specific substance of white crystals at a yield of 0.1333 g (yield: 97%).

Provenance & Evidence