Sodium Phosphate, Monobasic, Monohydrate → Pentasodium phosphate carbonate

Participants

Reaction Steps

Albumin (Human 25%, Plasbumin®-25 manufactured by Bayer Corporation) was buffered using differing amounts of Sodium Carbonate Monohydrate (Na2CO3H2O) (FW 124.00) (“Carbonate Buffer”) and Sodium Phosphate Monobasic Monohydrate (NaH2PO4H2O) (FW 137.99) (“Phosphate Buffer”). The buffered albumin formulations (2 cc) were mixed with 2 cc of the Shearwater PEG (0.45 g of PEG suspended in 2.2 cc of water), to provide 17% w/w PEG solids. The components were mixed by using the catheter device as generally shown in FIG. 2 (and as will be described in greater detail later). Upon mixing, the components were deposited in a test dish. The pH of the buffered albumin formulation (albumin plus buffer material) and the gelation time (as described above) and were recorded.

Provenance & Evidence