Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Piperidineethanol → 2-[1-(6-Chloro-2-quinolyl)-4-piperidyl]ethanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Piperidineethanol | HCID 73953 | — |
| 반응물 | 2,6-Dichloroquinoline | HCID 607502 | — |
| 생성물 | 2-[1-(6-Chloro-2-quinolyl)-4-piperidyl]ethanol | HCID 21096926 | — |
반응 단계
The process is performed as described in Example 4 (step 4.1). Starting with 2 g (10.10 mmol) of 2,6-dichloroquinoline and 1.44 g (11.10 mmol) of 2-(4-piperidyl)ethanol, and after chromatography on silica gel, eluting with a 98/2 mixture of dichloromethane and methanol, 2.54 g of pure product are obtained in the form of a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08034818B2 |
| 출처 데이터셋 | uspto-grants-2011_10 |
| ORD ID | ord-135654d1d06b4750b8f4680c3061bee1 |
| 출처 메모 | uspto-grants-2011_10 |