Anthranilic Acid → 2-[(2-Bromo-pyridin-4-ylmethyl)-amino]benzoic Acid

HRID 1663075Notes

Reaction equation

HRID 1663075 reaction equation
[C:1]([OH:10])(=[O:9])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[NH2:4].[Br:11][C:12]1[CH:17]=[C:16]([CH:18]=O)[CH:15]=[CH:14][N:13]=1>>[Br:11][C:12]1[CH:17]=[C:16]([CH2:18][NH:4][C:3]2[CH:5]=[CH:6][CH:7]=[CH:8][C:2]=2[C:1]([OH:10])=[O:9])[CH:15]=[CH:14][N:13]=1

Participants

3

Reactant 2

HCID 227Anthranilic AcidHCID 27629912-Bromo-4-pyridinecarboxaldehyde

Product 1

HCID 231189932-[(2-Bromo-pyridin-4-ylmethyl)-amino]benzoic Acid

Procedure

Prepared by a similar procedure as described for preparation 1A, starting from anthranilic acid and 2-bromo-pyridine-4-carbaldehyde (prepared as described in WO 2004/013102 A1).

Workup

  1. customPrepared by a similar procedure

Sources & evidence

ORD record
ord-fe7fcbc31d644e4cb3ce56e5a7832455
Source dataset
uspto-grants-2011_10
Patent number
US08034811B2

Reaction notes

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