HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Hexynenitrile → N-[3-(5-Cyano-pent-1-ynyl)-benzyloxy]-2-[(pyridin-4-ylmethyl)-amino]-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Hexynenitrile | HCID 139852 | — |
| Reactant | N-(3-Iodo-benzyloxy)-2-[(pyridin-4-ylmethyl)-amino]-benzamide | HCID 58989772 | — |
| Catalyst | Tetrabutylammonium Iodide | HCID 67553 | — |
| Product | N-[3-(5-Cyano-pent-1-ynyl)-benzyloxy]-2-[(pyridin-4-ylmethyl)-amino]-benzamide | HCID 11362277 | — |
Reaction Steps
The same procedure was used as described for the preparation of example 365, but without addition of tetrabutylammonium iodide. Starting materials: N-(3-Iodo-benzyloxy)-2-[(pyridin-4-ylmethyl)-amino]-benzamide (see example 361) and 5-cyano-1-pentyne (Aldrich).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08034811B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-36bd0d95c4e84b2c800cf7e17d8ea317 |
| Source note | uspto-grants-2011_10 |