HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Ethynyl-1-methyl-1H-imidazole → N-[2-(3-Methyl-3H-imidazol-4-ylethynyl)-benzyloxy]-2-[(pyridin-4-ylmethyl)-amino]-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Ethynyl-1-methyl-1H-imidazole | HCID 3333106 | — |
| Reactant | N-((2-iodobenzyl)oxy)-2-((pyridin-4-ylmethyl)amino)benzamide | HCID 11487973 | — |
| Product | N-[2-(3-Methyl-3H-imidazol-4-ylethynyl)-benzyloxy]-2-[(pyridin-4-ylmethyl)-amino]-benzamide | HCID 11316538 | — |
Reaction Steps
Starring materials: N-(2-Iodo-benzyloxy)-2-[(pyridin-4-ylmethyl)-amino]-benzamide (see Example 360) and 5-ethynyl-1-methyl-1-H-imidazole (Aldrich).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08034811B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-56b14976577647638fccbbae62e1d431 |
| Source note | uspto-grants-2011_10 |