HCID 25137665, compound → HCID 11314583, compound

HRID 1663150Notes

Reaction equation

HRID 1663150 reaction equation
FC1C(O[C:9](=[O:24])[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[NH:16][CH2:17][C:18]2[CH:23]=[CH:22][N:21]=[CH:20][CH:19]=2)=C(F)C(F)=C(F)C=1F.[CH2:29]([C:32]1[CH:36]=[C:35]([CH2:37][O:38][NH2:39])[O:34][N:33]=1)[CH2:30][CH3:31]>>[CH2:29]([C:32]1[CH:36]=[C:35]([CH2:37][O:38][NH:39][C:9](=[O:24])[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[NH:16][CH2:17][C:18]2[CH:19]=[CH:20][N:21]=[CH:22][CH:23]=2)[O:34][N:33]=1)[CH2:30][CH3:31]

Participants

3

Reactant 2

HCID 25137665HCID 25137665, compoundHCID 58989934HCID 58989934, compound

Product 1

HCID 11314583HCID 11314583, compound

Procedure

Prepared by the same method as described for example 415. Starting materials: 2-[(Pyridin-4-ylmethyl)-amino]-benzoic acid pentafluorophenyl ester (preparation 7C) and O-(3-Propyl-isoxazol-5-ylmethyl)-hydroxylamine (see preparation 63).

Workup

  1. customPrepared by the same method

Sources & evidence

ORD record
ord-365d311f09b74359b31569dc21c45199
Source dataset
uspto-grants-2011_10
Patent number
US08034811B2

Reaction notes

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