HCID 25137672, compound → HCID 11151978, compound
Reaction equation
FC1C(O[C:9](=[O:24])[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[NH:16][CH2:17][C:18]2[CH:23]=[CH:22][N:21]=[CH:20][CH:19]=2)=C(F)C(F)=C(F)C=1F.[CH3:29][C:30]1[CH2:34][CH:33]([CH2:35][O:36][NH2:37])[O:32][N:31]=1>>[CH3:29][C:30]1[CH2:34][CH:33]([CH2:35][O:36][NH:37][C:9](=[O:24])[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[NH:16][CH2:17][C:18]2[CH:19]=[CH:20][N:21]=[CH:22][CH:23]=2)[O:32][N:31]=1Participants
3
Procedure
Prepared by a similar method as described for example 415. Starting materials: 2-[(Pyridin-4-ylmethyl)-amino]-benzoic acid pentafluorophenyl ester (preparation 7C) and O-(3-methyl-4,5-dihydro-isoxazol-5-ylmethyl)-hydroxylamine (see preparation 89).
Workup
- customPrepared by a similar method
Sources & evidence
- ORD record
- ord-8a781c69ec8345ceb6dbd21ed897a8ac
- Source dataset
- uspto-grants-2011_10
- Patent number
- US08034811B2
Reaction notes
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