HCID 58989934, compound → HCID 58989837, compound

HRID 1663153Notes

Reaction equation

HRID 1663153 reaction equation
FC1C(O[C:9](=[O:24])[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[NH:16][CH2:17][C:18]2[CH:23]=[CH:22][N:21]=[CH:20][CH:19]=2)=C(F)C(F)=C(F)C=1F.[CH2:29]([C:31]1[CH2:35][CH:34]([CH2:36][O:37][NH2:38])[O:33][N:32]=1)[CH3:30]>>[CH2:29]([C:31]1[CH2:35][CH:34]([CH2:36][O:37][NH:38][C:9](=[O:24])[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[NH:16][CH2:17][C:18]2[CH:19]=[CH:20][N:21]=[CH:22][CH:23]=2)[O:33][N:32]=1)[CH3:30]

Participants

3

Reactant 2

HCID 58989934HCID 58989934, compoundHCID 58990013O-(3-ethyl-4,5-dihydro-isoxazol-5-ylmethyl)-hydroxylamine

Product 1

HCID 58989837HCID 58989837, compound

Procedure

Prepared by a similar method as described for example 415. Starting materials: 2-[(Pyridin-4-ylmethyl)-amino]-benzoic acid pentafluorophenyl ester (preparation 7C) and O-(3-ethyl-4,5-dihydro-isoxazol-5-ylmethyl)-hydroxylamine (see preparation 90).

Workup

  1. customPrepared by a similar method

Sources & evidence

ORD record
ord-25f316d88cc643409fe9ef5207f3dcf6
Source dataset
uspto-grants-2011_10
Patent number
US08034811B2

Reaction notes

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