Benzyloxyamine hydrochloride → N-Benzyloxy-2-[(5-oxo-4,5-dihydro-1H-[1,2,4]triazol-3-ylmethyl)-amino]-benzamide

HRID 1663178Notes

Reaction equation

HRID 1663178 reaction equation
[O:1]=[C:2]1[NH:6][N:5]=[C:4]([CH2:7][N:8]2[C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=3[C:11](=[O:18])OC2=O)[NH:3]1.Cl.[CH2:21]([O:28][NH2:29])[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[CH2:21]([O:28][NH:29][C:11](=[O:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[NH:8][CH2:7][C:4]1[NH:3][C:2](=[O:1])[NH:6][N:5]=1)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1

Participants

3

Reactant 2

HCID 102312Benzyloxyamine hydrochlorideHCID 1361574361-(5-Oxo-4,5-dihydro-1H-[1,2,4]triazol-3-ylmethyl)-1H-benzo[d][1,3]oxazine-2,4-dione

Product 1

HCID 136157435N-Benzyloxy-2-[(5-oxo-4,5-dihydro-1H-[1,2,4]triazol-3-ylmethyl)-amino]-benzamide

Procedure

Starting materials: 1-(5-Oxo-4,5-dihydro-1H-[1,2,4]triazol-3-ylmethyl)-1H-benzo[d][1,3]oxazine-2,4-dione (see preparation 7E) and O-benzyl-hydroxylamine hydrochloride (Aldrich).

Sources & evidence

ORD record
ord-981e16040c124e1aa39ce0b668964965
Source dataset
uspto-grants-2011_10
Patent number
US08034811B2

Reaction notes

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