Hydrochloric Acid → HCID 24745015, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of Compound 1 (0.5 g, 1.8 mmol) in 10 mL of MeOH/1N NaOH aq. solution (1:1) was added MeI (2 mL). The mixture was stirred at 80° C. in sealed tube overnight. The mixture was neutralized with concentrated HCl. Extracted by EtOAc and dried over MgSO4. Removing solvent gave the crude acid product, which used for next step without further purification. [M+H] calc'd for C15H18N2O4, 291; found, 291.

Provenance & Evidence