HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethyl phosphite → Diethyl (4-Cyanobenzyl)phosphonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethyl phosphite | HCID 31215 | — |
| Reactant | 4-(Bromomethyl)benzonitrile | HCID 86996 | — |
| Product | Diethyl (4-Cyanobenzyl)phosphonate | HCID 241438 | 97% |
Reaction Steps
A mixture of 4-cyano-benzyl bromide (41.8 g, 0.213 mol) and triethyl phosphite (42 mL, 0.244 mol) was stirred in a flask equipped with a Dean-Stark trap at 150° C. for 6 h, then the reaction mixture was submitted to distillation in vacuo to yield 52.2 g (97%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08034827B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-ffaf4e3d146d4dc8839ee9a51a75c33c |
| Source note | uspto-grants-2011_10 |