HCID 23627640, compound → HCID 67435795, compound

HRID 1663247Notes

Reaction equation

[Cl:1][C:2]1[CH:3]=[C:4]([S:9]([N:12]2[CH:25]([CH2:26][C:27]([OH:29])=O)[C:24]3[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=3)[C:18]3[CH:17]=[CH:16][CH:15]=[CH:14][C:13]2=3)(=[O:11])=[O:10])[CH:5]=[CH:6][C:7]=1[Cl:8].[NH:30]1[CH2:35][CH2:34][CH:33]([CH2:36][C:37]2[CH:42]=[CH:41][C:40]([C:43]3[NH:44][CH2:45][CH2:46][CH2:47][N:48]=3)=[CH:39][CH:38]=2)[CH2:32][CH2:31]1>>[Cl:1][C:2]1[CH:3]=[C:4]([S:9]([N:12]2[CH:25]([CH2:26][C:27]([N:30]3[CH2:35][CH2:34][CH:33]([CH2:36][C:37]4[CH:38]=[CH:39][C:40]([C:43]5[NH:48][CH2:47][CH2:46][CH2:45][N:44]=5)=[CH:41][CH:42]=4)[CH2:32][CH2:31]3)=[O:29])[C:24]3[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=3)[C:18]3[CH:17]=[CH:16][CH:15]=[CH:14][C:13]2=3)(=[O:10])=[O:11])[CH:5]=[CH:6][C:7]=1[Cl:8]

Participants

Reactant 2

HCID 23627640HCID 23627640, compound

HCID 67436512HCID 67436512, compound

Product 1

HCID 67435795HCID 67435795, compound

Procedure

The title compound was prepared from [5-(3,4-dichloro-benzenesulfonyl)-5,6-dihydro-phenanthridin-6-yl]-acetic acid (Example 2c) and 2-(4-piperidin-4-ylmethyl-phenyl)-1,4,5,6-tetrahydro-pyrimidine (Reference Example 7) according to the method described in Example 1e. MS (EI) 688.3 (MH+).

Sources & evidence

ORD record: ord-abe55db9dcb64aab9b5963677c71f19b
Source dataset: uspto-grants-2011_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08034827B2

Reaction notes

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