HCID 67436512, compound → HCID 67437254, compound

HRID 1663249Notes

Reaction equation

[Cl:1][C:2]1[CH:3]=[C:4]([S:9]([N:12]2[CH:25]([CH2:26][C:27]([OH:29])=O)[C:24]3[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=3)[C:18]3[CH:17]=[CH:16][CH:15]=[CH:14][C:13]2=3)(=[O:11])=[O:10])[CH:5]=[CH:6][C:7]=1[Cl:8].ClC1C=C(S(C2[C:54]3[C:53]4[C:48](=CC=CC=4)[CH:47]([CH:55]4CN(CCNC(=O)C)CC[N:56]4[C:67]4[CH:72]=[CH:71][N:70]=[CH:69][CH:68]=4)NC=3C=CC=2)(=O)=O)C=CC=1Cl>>[N:56]1([CH:67]2[CH2:68][CH2:69][N:70]([CH2:17][CH2:18][CH2:13][NH:12][C:27](=[O:29])[CH2:26][CH:25]3[C:20]4[C:19](=[CH:24][CH:23]=[CH:22][CH:21]=4)[C:18]4[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=4[N:12]3[S:9]([C:4]3[CH:5]=[CH:6][C:7]([Cl:8])=[C:2]([Cl:1])[CH:3]=3)(=[O:11])=[O:10])[CH2:71][CH2:72]2)[CH2:55][CH2:47][CH2:48][CH2:53][CH2:54]1

Participants

Reactant 2

HCID 67436512HCID 67436512, compound

HCID 86761429HCID 86761429, compound

Product 1

HCID 67437254HCID 67437254, compound

Procedure

The title compound was prepared from [5-(3,4-dichloro-benzenesulfonyl)-5,6-dihydro-phenanthridin-6-yl]-acetic acid (Example 2c) and 3-[1,4′]bipiperidinyl-1′-yl)-propylamine trihydrochloride (Reference Example 3) according to the method described in Example 1e. MS (EI) 655.68 (MH+).

Sources & evidence

ORD record: ord-6e76e1930f514f21abfb8b1a8e9472a0
Source dataset: uspto-grants-2011_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08034827B2

Reaction notes

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