HCID 67217405, compound → HCID 23627580, compound

HRID 1663261Notes

Reaction equation

[C:1]([C:4]1[CH:5]=[C:6]2[C:15](=[CH:16][CH:17]=1)[C:14]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[N:8]([S:18]([C:21]1[CH:26]=[CH:25][C:24]([Cl:27])=[C:23]([Cl:28])[CH:22]=1)(=[O:20])=[O:19])[CH:7]2[CH2:29][C:30]([OH:32])=O)(=[O:3])[CH3:2].Cl.Cl.[NH:35]1[CH2:39][CH2:38][N:37]=[C:36]1[C:40]1[CH:45]=[CH:44][C:43]([CH2:46][CH2:47][NH2:48])=[CH:42][CH:41]=1>>[ClH:27].[C:1]([C:4]1[CH:5]=[C:6]2[C:15](=[CH:16][CH:17]=1)[C:14]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[N:8]([S:18]([C:21]1[CH:26]=[CH:25][C:24]([Cl:27])=[C:23]([Cl:28])[CH:22]=1)(=[O:19])=[O:20])[CH:7]2[CH2:29][C:30]([NH:48][CH2:47][CH2:46][C:43]1[CH:44]=[CH:45][C:40]([C:36]2[NH:37][CH2:38][CH2:39][N:35]=2)=[CH:41][CH:42]=1)=[O:32])(=[O:3])[CH3:2]

Participants

Reactant 2

HCID 67217405HCID 67217405, compound

HCID 67436619HCID 67436619, compound

Product 1

HCID 23627580HCID 23627580, compound

Procedure

The title compound was prepared from [8-acetyl-5-(3,4-dichloro-benzenesulfonyl)-5,6-dihydro-phenanthridin-6-yl]-acetic acid and 2-[4-(4,5-dihydro-1H-imidazol-2-yl)-phenyl]-ethylamine dihydrochloride (Reference Example 2) according to the method described in Example 1e. MS (EI) 662.3 (MH+).

Sources & evidence

ORD record: ord-b038084aaf0c4a999bfc938343050264
Source dataset: uspto-grants-2011_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08034827B2

Reaction notes

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