HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromo-4-hydroxy-5-nitrobenzaldehyde → HCID 67435380, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromo-4-hydroxy-5-nitrobenzaldehyde | HCID 1494378 | — |
| Reactant | 5-Propylcyclohexane-1,3-dione | HCID 2737224 | — |
| Reactant | 3-Aminocrotonitrile | HCID 5324720 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 67435380 | HCID 67435380 | — |
Reaction Steps
A mixture of 3-bromo-4-hydroxy-5-nitro-benzaldehyde (2 g), 3-aminocrotonitrile (667 mg) and 5-propylcyclohexane-1,3-dione (1.25 g) in ethanol (75 ml) was heated to reflux for 17 h. The mixture was concentrated in vacuo. The residue was purified by chromatography on silicagel in heptane/ethyl acetate 1/0→0/1 (v/v) as eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08034945B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-76a27bf88529460d9d013dd0221cab81 |
| Source note | uspto-grants-2011_10 |