Nitric Acid → 3-Ethoxy-4-hydroxy-5-nitrobenzaldehyde

HRID 1663369Notes

Reaction equation

HRID 1663369 reaction equation
[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][C:11]=1[OH:12])[CH:7]=[O:8])[CH3:2].[N+:13]([O-])([OH:15])=[O:14]>C(O)(=O)C>[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([CH:9]=[C:10]([N+:13]([O-:15])=[O:14])[C:11]=1[OH:12])[CH:7]=[O:8])[CH3:2]

Participants

4

Reactant 2

HCID 944Nitric AcidHCID 8467Ethylvanillin

Product 1

HCID 5848783-Ethoxy-4-hydroxy-5-nitrobenzaldehyde

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

To a solution of 3-ethoxy-4-hydroxybenzaldehyde (5 g) in acetic acid (50 ml) was added nitric acid (1.4 ml) in 2 portions. The resulting suspension was stirred for 17 h. The solid was collected by filtration, washed with water and dried in vacuo.

Workup

  1. filtrationThe solid was collected by filtration
  2. washwashed with water
  3. customdried in vacuo

Sources & evidence

ORD record
ord-b8e7415bd6154ebd82f586b870b2b067
Source dataset
uspto-grants-2011_10
Patent number
US08034945B2

Reaction notes

Loading…