HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1663385Generated: October 29, 2026
3-Bromo-4-hydroxy-5-nitrobenzaldehyde → HCID 67435380, compound
https://huagongshe.com/reaction/1663385
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Bromo-4-hydroxy-5-nitrobenzaldehyde | HCID 1494378 | — |
| Reactant | 5-Propylcyclohexane-1,3-dione | HCID 2737224 | — |
| Reactant | 3-Aminocrotonitrile | HCID 5324720 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 67435380 | HCID 67435380 | — |
Reaction Steps
A mixture of 3-bromo-4-hydroxy-5-nitro-benzaldehyde (18.26 g), 3-aminocrotonitrile (6.09 g) and 5-propylcyclohexane-1,3-dione (11.45 g) in ethanol (250 ml) was stirred at 80° C. for 17 h. The mixture was concentrated in vacuo. The residue was purified by chromatography on silicagel in dichloromethane as eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08034945B2 |
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| Source dataset | uspto-grants-2011_10 |
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| ORD ID | ord-5ded5b8bd1f84c27b4dbc561ba532673 |
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| Source note | uspto-grants-2011_10 |
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