Acetic Acid → HCID 67434330, compound

Participants

Reaction Steps

To a solution of N-[2-bromo-4-(3-cyano-2-methyl-5-oxo-7-propyl-1,4,5,6,7,8-hexahydro-quinolin-4-yl)-6-(propane-1-sulfonylamino)-phenyl]-3-nitro-benzamide (412 mg) and acetic acid (520 μl) in THF (10 ml), cooled to 0° C., was added zinc dust (810 mg) under vigorous stirring. After stirring for 4 h, the mixture was filtered and concentrated in vacuo. The residue was dissolved in dichloromethane and washed with water. The organic layer was dried (MgSO4), filtered and concentrated in vacuo.

Provenance & Evidence