反应详情

温度

80 °C

A mixture of 3-bromo-4-hydroxy-benzaldehyde (13.07 g), 5-propylcyclohexane-1,3-dione (10.02 g) and 3-aminocrotonitrile (5.34 g) in ethanol (165 ml) was stirred at 80° C. for 17 h. A precipitate formed, which was collected by filtration. The filtrate was concentrated in vacuo and then triturated with ethyl acetate. The solids were combined and dried in vacuo.

1. customA precipitate formed
2. filtrationwhich was collected by filtration
3. concentrationThe filtrate was concentrated in vacuo
4. customtriturated with ethyl acetate
5. customdried in vacuo