HCID 20747587, compound → HCID 58091579, compound

Participants

Reaction Steps

A mixture of 4-acetyl-N,N-dimethylbenzamide (9.80 g, 51.2 mmol) and DMF dimethyl acetal (60 mL) was heated to reflux for 15 h, cooled to room temperature and concentrated. The residue was recrystallized from ethyl acetate to give (E)-4-(3-(dimethylamino)acryloyl)-N,N-dimethylbenzamide as a brown solid (8.80 g, 70%). MS (E+) m/z: 247 (M+H).

Provenance & Evidence