1-(Trifluoroacetyl)piperidine-4-carbonyl chloride → N-{4-[4-(3-Bromo-4-fluorophenyl)-5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl]-1,2,5-oxadiazol-3-yl}-1-(trifluoroacetyl)piperidine-4-carboxamide

Participants

Role	Name	HCID	Charge
Reactant	1-(Trifluoroacetyl)piperidine-4-carbonyl chloride	HCID 11085989	—
Reactant	3-(4-amino-1,2,5-oxadiazol-3-yl)-4-(3-bromo-4-fluorophenyl)-1,2,4-oxadiazol-5(4H)-one	HCID 59148388	—
Product	N-{4-[4-(3-Bromo-4-fluorophenyl)-5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl]-1,2,5-oxadiazol-3-yl}-1-(trifluoroacetyl)piperidine-4-carboxamide	HCID 58755137	—

Reaction Steps

This compound was prepared according to the procedure of Example 35, Step 2, using 3-(4-amino-1,2,5-oxadiazol-3-yl)-4-(3-bromo-4-fluorophenyl)-1,2,4-oxadiazol-5(4H)-one and 1-(trifluoroacetyl)piperidine-4-carbonyl chloride as the starting materials. LCMS for C18H14BrF4N6O5 (M+H)+: m/z=549.0, 550.9.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08034953B2
Source dataset	uspto-grants-2011_10
ORD ID	ord-48439e39dede49e68d71458888ccef04
Source note	uspto-grants-2011_10