HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,3-Dimethylbutanal → Aspartame
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,3-Dimethylbutanal | HCID 76335 | — |
| Reactant | Bisulfite | HCID 104748 | — |
| Reactant | Neotame | HCID 9810996 | — |
| Product | Aspartame | HCID 134601 | — |
| Product | Neotame | HCID 9810996 | — |
Reaction Steps
In a second embodiment of the present invention, neotame is synthesized by first hydrolyzing a bisulfite adduct of 3,3-dimethylbutyraldehyde with a base in a solvent or a mixture of solvents and then adding aspartame under hydrogenation conditions with a catalyst to produce neotame.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08034969B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-ecbc724e18314f44aa365f74ae011570 |
| Source note | uspto-grants-2011_10 |