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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1663507Generated: October 31, 2026

3,3-Dimethylbutanal → Aspartame

https://huagongshe.com/reaction/1663507

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,3-DimethylbutanalHCID 76335—
ReactantNeotameHCID 9810996—
ProductAspartameHCID 134601—
ProductNeotameHCID 9810996—

Reaction Steps

In a fourth embodiment of the present invention, neotame is synthesized by hydrolyzing a trimer of 3,3-dimethylbutyraldehyde with an acid in a solvent or a mixture of solvents and then adding aspartame under hydrogenation conditions with a catalyst to produce neotame.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08034969B2
Source datasetuspto-grants-2011_10
ORD IDord-4a4e74e27a1d4c8db357a18d5a62ed47
Source noteuspto-grants-2011_10