HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl orthoformate → 2-[2-oxo4-(1H-tetrazol-1-yl)-1-pyrrolidinyl]butanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl orthoformate | HCID 31214 | — |
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | HCID 22386994 | HCID 22386994 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2-[2-oxo4-(1H-tetrazol-1-yl)-1-pyrrolidinyl]butanamide | HCID 22387062 | — |
Reaction Steps
Alternatively to §5.6, reaction of 2-[4-amino-2-oxo-1-pyrrolidinyl]butanamide with triethyl orthoformate, NaN3 and AcOH provided 2-[2-oxo-4-(1H-tetrazol-1-yl)-1-pyrrolidinyl]butanamide 67.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08034958B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-88774dabce2c46e78fbb8bd77aa70b05 |
| Source note | uspto-grants-2011_10 |