HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methoxyacetyl chloride → N-(6-iodoimidazo[1,2-b]pyridazin-2-yl)-2-methoxyacetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methoxyacetyl chloride | HCID 96623 | — |
| Reactant | 6-Iodoimidazo[1,2-B]pyridazin-2-amine | HCID 57441024 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | N-(6-iodoimidazo[1,2-b]pyridazin-2-yl)-2-methoxyacetamide | HCID 57441027 | 79% |
Reaction Steps
Using 6-iodoimidazo[1,2-b]pyridazin-2-amine (1.0 g, 3.85 mmol), N,N-dimethylacetamide (10 mL) and methoxyacetyl chloride (0.46 g, 4.23 mmol) as starting materials and in the same manner as in Reference Example 5, the title compound (1.01 g, 79%) was obtained as a dark brown powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08034812B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-3053563462d9454cb9caf0ae07da07dc |
| Source note | uspto-grants-2011_10 |