Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1663674Generated: October 29, 2026

Iodoethane → methyl 3-ethoxy-1-methyl-1H-pyrazole-5-carboxylate

https://huagongshe.com/reaction/1663674

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodoethaneHCID 6340—
ReactantPotassium CarbonateHCID 11430—
ReactantHCID 178498598HCID 178498598—
SolventDimethylformamideHCID 6228—
Productmethyl 3-ethoxy-1-methyl-1H-pyrazole-5-carboxylateHCID 5744104994%

Reaction Steps

Using methyl 3-hydroxy-1-methyl-1H-pyrazole-5-carboxylate (2.34 g, 15.0 mmol), iodoethane (3.51 g, 22.5 mmol), potassium carbonate (4.15 g, 30.0 mmol) and N,N-dimethylformamide (15 mL), and in the same manner as in Reference Example 57, the title compound (2.59 g, yield 94%) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08034812B2
Source datasetuspto-grants-2011_10
ORD IDord-a40926337f784c2da0098cb2732c98d3
Source noteuspto-grants-2011_10