HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → methyl 3-(2-methoxyethoxy)-1-methyl-1H-pyrazole-5-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Bromoethyl methyl ether | HCID 80972 | — |
| Reactant | HCID 178498598 | HCID 178498598 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | methyl 3-(2-methoxyethoxy)-1-methyl-1H-pyrazole-5-carboxylate | HCID 57441051 | 94.3% |
Reaction Steps
Using methyl 3-hydroxy-1-methyl-1H-pyrazole-5-carboxylate (2.34 g, 15.0 mmol), 1-bromo-2-methoxyethane (3.13 g, 22.5 mmol), potassium carbonate (4.15 g, 30.0 mmol) and N,N-dimethylformamide (15 mL), and in the same manner as in Reference Example 57, the title compound (3.03 g, yield 94%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08034812B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-399c84d26d5b48ed9f07af3d92bcb111 |
| Source note | uspto-grants-2011_10 |