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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1663783Generated: October 29, 2026

Methanesulfonic Acid → HCID 86630644, compound

https://huagongshe.com/reaction/1663783

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanesulfonic AcidHCID 6395—
ReactantTak-593HCID 24767976—
SolventEthanolHCID 702—
ProductHCID 86630644HCID 8663064467%

Reaction Steps

Using N-[5-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)-2-methylphenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide (2.00 g, 4.49 mmol), ethanol (80 mL) and methanesulfonic acid (0.34 mL, 4.71 mmol), and in the same manner as in Example 152, the title compound (1.63 g, 67%) was obtained as white crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08034812B2
Source datasetuspto-grants-2011_10
ORD IDord-3390edf244814b99abbd8b2f94399a45
Source noteuspto-grants-2011_10