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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1664014Generated: October 30, 2026

Triethylamine → HCID 57386317, compound

https://huagongshe.com/reaction/1664014

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
ReactantCyclopentanecarbonyl chlorideHCID 78284—
ReactantN-{3-[(2-aminoimidazo[1,2-b]pyridazin-6-yl)oxy]phenyl}-3-(trifluoromethyl)benzamideHCID 57385788—
SolventTetrahydrofuranHCID 8028—
ProductHCID 57386317HCID 5738631757%

Reaction Steps

Using N-{3-[(2-aminoimidazo[1,2-b]pyridazin-6-yl)oxy]phenyl}-3-(trifluoromethyl)benzamide (150 mg, 0.362 mmol), cyclopentanecarbonyl chloride (53 μL, 0.435 mmol), triethylamine (75 μL, 0.544 mmol) and tetrahydrofuran (5 mL) as starting materials and in the same manner as in Example 388, the title compound (105 mg, 57%) was obtained as a white powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08034812B2
Source datasetuspto-grants-2011_10
ORD IDord-22c073aa8990416da0d152a77952123c
Source noteuspto-grants-2011_10