HCID 178418546, compound → HCID 178434593, compound

Participants

Reaction Steps

5-(2-Bromo-5-fluorophenyl)-3-methyl-1H-1,2,4-triazole (4.00 g, 15.6 mmol) was treated with copper (I) cyanide as described in the procedure for intermediate 150 to give 0.83 g (26% yield) of the title material as a white solid. 1HNMR 400 MHz (CDCl3) δ (ppm): 2.66 (3H, s, CH3), 7.21-7.25 (1H, m, aromatic), 7.84 (1H, dd, J=5.6 Hz and J=8.6 Hz, aromatic), 8.10 (1H, dd, J=2.8 Hz and J=9.3 Hz, aromatic). HRMS (ESI+) calculated for C10H8FN4 [M+H+]: 203.0733; found: 203.0743.

Provenance & Evidence