Acetic Acid → HCID 178475926, compound

Participants

Reaction Steps

4-Fluoro-2-(3-methyl-1H-1,2,4-triazol-5-yl)benzonitrile (0.803 g, 4.1 mmol) was hydrogenated as described in the procedure for intermediate 151 to give 0.796 g (73% yield) the title acetic acid salt as a white solid. 1HNMR 400 MHz (DMSO-d6) δ (ppm): 2.41 (3H, s, CH3), 3.97 (2H, s, CH2), 7.24 (1H, m, aromatic), 7.55 (1H, dd, J=6.1 Hz and J=8.1 Hz, aromatic), 7.66 (1H, dd, J=2.8 Hz and J=10.3 Hz, aromatic). HRMS (ESI+) calculated for C10H12FN4 [M+H+]: 207.1046; found: 207.1049.

Provenance & Evidence