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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1664566Generated: October 29, 2026

HCID 178446151, compound → 9-pentyl-3-[2-(5-phenyl-1,3,4-oxadiazol-2-yl)ethyl]-6,9-dihydro-5H-[1,2,4]triazolo[4,3-a]purin-5-one

https://huagongshe.com/reaction/1664566

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178446151HCID 178446151—
SolventTolueneHCID 1140—
Product9-pentyl-3-[2-(5-phenyl-1,3,4-oxadiazol-2-yl)ethyl]-6,9-dihydro-5H-[1,2,4]triazolo[4,3-a]purin-5-oneHCID 5760025966.7%

Reaction Steps

The mixture of N′-[(2E)-6-oxo-3-pentyl-1,3,6,7-tetrahydro-2H-purin-2-ylidene]-3-(5-phenyl-1,3,4-oxadiazol-2-yl)propanohydrazide (485 mg, 1.11 mmol) in toluene (50 mL) was heated to reflux overnight. The mixture was concentrated to yield the desired product (310 mg, 66.7%). LCMS calculated for C21H23N8O2 (M+H): 419.2. found 419.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08039478B2
Source datasetuspto-grants-2011_10
ORD IDord-3236ced2cc7e4cab8c502f3345d90cf4
Source noteuspto-grants-2011_10