HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178446151, compound → 9-pentyl-3-[2-(5-phenyl-1,3,4-oxadiazol-2-yl)ethyl]-6,9-dihydro-5H-[1,2,4]triazolo[4,3-a]purin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178446151 | HCID 178446151 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 9-pentyl-3-[2-(5-phenyl-1,3,4-oxadiazol-2-yl)ethyl]-6,9-dihydro-5H-[1,2,4]triazolo[4,3-a]purin-5-one | HCID 57600259 | 66.7% |
Reaction Steps
The mixture of N′-[(2E)-6-oxo-3-pentyl-1,3,6,7-tetrahydro-2H-purin-2-ylidene]-3-(5-phenyl-1,3,4-oxadiazol-2-yl)propanohydrazide (485 mg, 1.11 mmol) in toluene (50 mL) was heated to reflux overnight. The mixture was concentrated to yield the desired product (310 mg, 66.7%). LCMS calculated for C21H23N8O2 (M+H): 419.2. found 419.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08039478B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-3236ced2cc7e4cab8c502f3345d90cf4 |
| Source note | uspto-grants-2011_10 |