HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57600319, compound → HCID 57600282, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57600319 | HCID 57600319 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 57600282 | HCID 57600282 | — |
Reaction Steps
A mixture of 3-(3,3-diethoxypropyl)-5-(4-methoxyphenyl)-1,2,4-oxadiazole (1.0 g, 3.0 mmol) in 2N HCl (10 mL) and THF (10 mL) was stirred at room temperature overnight. The reaction mixture was extracted with EtOAc (3×). The organic layers were washed with water, dried over Na2SO4, filtered and concentrated to give the desired product. LCMS calculated for C12H13N2O3 (M+H): 233.1. found: 233.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08039478B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-283e8714dd3f49c3b4bba5122d9035d6 |
| Source note | uspto-grants-2011_10 |