Boron tribromide → HCID 57600208, compound

Participants

Reaction Steps

To a solution of N-[2-(7-bromo-5-oxo-9-pentyl-6,9-dihydro-5H-[1,2,4]triazolo[4,3-a]purin-3-yl)ethyl]-4-methoxybenzamide (63.0 mg, 0.125 mmol) in CH2Cl2 (5 mL) at 0° C. was added a solution of Boron tribromide in CH2Cl2 (1.0 M, 1.3 mL, 1.3 mmol). The mixture was stirred at room temperature overnight. The reaction mixture was quenched with water and then concentrated and purified by preparative LCMS to give the desired product. LCMS calculated for C20H23BrN7O3 (M+H): m/z=488.1, 490.1. found: 488.0, 489.9.

Provenance & Evidence