HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Chlorophenyl)(3-fluorophenyl)methanol → Carbonic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl)ester (3-chloro-phenyl)-(3-fluoro-phenyl)-methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Chlorophenyl)(3-fluorophenyl)methanol | HCID 2757532 | — |
| Reactant | imidazole-1-carboxylic acid (R)-1-aza-bicyclo[2.2.2]oct-3-yl ester | HCID 59187189 | — |
| Product | Carbonic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl)ester (3-chloro-phenyl)-(3-fluoro-phenyl)-methyl ester | HCID 86638971 | — |
Reaction Steps
The desired product was prepared by reacting imidazole-1-carboxylic acid (R)-1-aza-bicyclo[2.2.2]oct-3-yl ester with (3-chloro-phenyl)-(3-fluoro-phenyl)-methanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08039483B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-65939bc0e697497e90900525d31e5fe0 |
| Source note | uspto-grants-2011_10 |