HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl 4-(3-oxo-2,3-dihydropyridazin-4-yl)piperidine-1-carboxylate → HCID 57562526, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl 4-(3-oxo-2,3-dihydropyridazin-4-yl)piperidine-1-carboxylate | HCID 67439720 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 57562526 | HCID 57562526 | 90.1% |
Reaction Steps
A solution of benzyl 4-(3-oxo-2,3-dihydropyridazin-4-yl)piperidine-1-carboxylate (0.90 mg, 2.88 mmol) and 10% Pd/C (500 mg) in ethanol (25 mL), was hydrogenated under a balloon for 4 h. The reaction was filtered through celite, washed with ethanol and concentrated to give the title compound (465 mg). MS 180.1 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08039460B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-ed653b2a96dd4bd9a26315893932faf8 |
| Source note | uspto-grants-2011_10 |