Hydrazine → HCID 178438879, compound

Participants

Reaction Steps

Hydrazine (anhydrous; 1.11 mL, 35.40 mmol) was added to a solution of 3-allyl-6-(2,3-difluorophenyl)azepane-2-thione (249 mg, 0.885 mmol) in ethanol (8 mL). After 4 h, the reaction mixture was concentrated. The residue was diluted with saturated aqueous sodium bicarbonate and extracted with dichloromethane (3×). The organic extracts were dried over sodium sulfate, filtered and concentrated to give the title compound. (MS 280.2 (M+1).

Provenance & Evidence