Cesium carbonate → HCID 25234320, compound

Participants

Reaction Steps

In analogy to example 10, step 3, propane-2-sulfonic acid (3′-methanesulfonyl-biphenyl-3-ylmethyl)-amide (example 49, step 2) was reacted with 4-fluorobenzyl bromide, tetrabutylammonium iodide and cesium carbonate in N,N-dimethylacetamide to give propane-2-sulfonic acid (4-fluoro-benzyl)-(3′-methanesulfonyl-biphenyl-3-ylmethyl)-amide as a colorless solid. MS: 493.3 ([M+NH4]+)

Provenance & Evidence