HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → HCID 67086991, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | 1-Boc-D-Pyroglutamic acid ethyl ester | HCID 820885 | — |
| Reactant | 1-Bromo-4-(tert-butoxy)benzene | HCID 2763959 | — |
| Product | HCID 67086991 | HCID 67086991 | — |
Reaction Steps
(R)-2-tert-Butoxycarbonylamino-5-(4-tert-butoxy-phenyl)-pentanoic acid ethyl ester is prepared according to the procedure of Ding, Chuanyong.; Ma, Rujian.; Rong, Guobin. Preparation of w-Phenyl-(2S)—N-Boc-amino Acid Ethyl esters; Chinese Journal of Organic Chemistry Vol 26(12) 2006, 1694 &1695, replacing Ethyl Boc-L-pyroglutamate with Ethyl Boc-D-pyroglutamate & Bromomethyl-benzene with 1-Bromo-4-tert-butoxy-benzene in Example 2a, using preparation steps 2.2, 2.3, and 2.5; [M+H]+ 394
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08039472B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-56640144144444dfaf52bdfe79f35df8 |
| Source note | uspto-grants-2011_10 |