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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1665164Generated: October 31, 2026

Methyl 6-aminonicotinate → 6-(3-Isopropylureido)nicotinic acid

https://huagongshe.com/reaction/1665164

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 6-aminonicotinateHCID 737487—
ReactantEthyl 2-aminopyridine-4-carboxylateHCID 7015521—
Reactant2-(3-Isopropyl-ureido)-isonicotinic acidHCID 64393466—
Product6-(3-Isopropylureido)nicotinic acidHCID 61319003—

Reaction Steps

This compound is prepared analogously to Intermediate Y by replacing ethyl 2-aminoisonicotinate in step 1 with methyl 6-aminonicotinate; [M+H]+ 224.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08039472B2
Source datasetuspto-grants-2011_10
ORD IDord-cb064c8d02884ce9b699ce9388f1ec47
Source noteuspto-grants-2011_10