p-Toluenesulfonic acid → HCID 86634954, compound

Participants

Reaction Steps

Under nitrogen atmosphere, a mixture of 0.74 g of t-butyl (1R)-trans-3-[(E)-3-(2-propenyloxyimino)-2-methyl-1-propenyl]-2,2-dimethylcyclopropanecarboxylate, catalytic amount of p-toluenesulfonic acid and 10 ml of toluene was stirred for 1 hour under reflux. The reaction mixture was cooled down to room temperature, then, concentrated under reduced pressure. The residue was subjected to silica gel column chromatography to obtain 0.47 g of (1R)-trans-3-[(E)-3-(2-propenyloxyimino)-2-methyl-1-propenyl]-2,2-dimethylcyclopropanecarboxylic acid:

Provenance & Evidence