Pyridine-4-carbonyl chloride → HCID 57661907, compound

Participants

Reaction Steps

Compound 57 was synthesized using spiro[naphtho[1,2-b][1,4]oxathiine-2,4′-piperidine]-5,6-dione, isonicotinoyl chloride and conditions outlined in procedure N. M.p.=267-269° C.; 400 MHz 1H NMR (CDCl3) δ 8.73 (d, J=6 Hz, 2H), 8.08 (d, J=8 Hz, 1H), 7.75 (m, 1H), 7.70 (m, 1H), 7.66 (t, 1H), 7.52 (t, J=7.6 Hz, 2H), 4.68 (d, J=12 Hz, 1H), 3.63 (m, 1H), 3.50 (m 1H), 3.37 (m, 1H), 2.98 (d, 7.6 Hz, 2H), 2.28 (brm, 1H), 2.14 (brm, 1H), 1.91 (brm, 1H), 1.73 (brm, 1H); LCMS: 407 [M+H].

Provenance & Evidence