5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1-carboxylic acid → HCID 57661871, compound

Participants

Reaction Steps

Compound 73 was synthesized using spiro[naphtho[1,2-b][1,4]oxathiine-2,4′-piperidine]-5,6-dione, 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1-carboxylic acid conditions outlined in procedure O. M.p.=265-267° C.; 400 MHz 1H NMR (DMSO-d6) δ: 7.92 (dd, J=0.78, 7.4 Hz, 2H), 7.76-7.80 (m, 2H), 7.59 (t, J=7.4 Hz, 1H), 7.49 (d, J=8.2 Hz, 1H), 7.05 (t, J=7.8 Hz, 1H), 6.93 (d, J=7.0 Hz, 1H), 4.22 (m, 4H), 3.45 (t, J=11.4 Hz, 2H), 3.16 (s, 2H), 2.95 (t, J=5.8 Hz, 2H), 2.06-2.16 (m, 4H), 1.87 (m 2H); LCMS=485 [M+H].

Provenance & Evidence